Laboratory Workup

Essential laboratory tests in the initial diagnostic workup of lymphoma are1:

  • Complete blood count (CBC) with differential
  • Comprehensive metabolic panel (CMP)
  • Lactate dehydrogenase (LDH) test
  • Hepatitis B screen
  • Pregnancy test (if patient is of childbearing age and if chemotherapy or radiation therapy [RT] is planned)

Laboratory tests that are useful in select cases include1:

  • Serum protein electrophoresis (SPEP; measures specific proteins in the blood to help identify specific diseases) and/or quantitative immunoglobulins (measures of antibody proteins in blood)
  • Hepatitis C screen
  • Uric acid
  • Beta-2 microglobulin (B2M) test

Reference: 1. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for B-Cell Lymphomas V.4.2019. © National Comprehensive Cancer Network, Inc. 2019. All rights reserved. Accessed July 10, 2019. To view the most recent and complete version of the guideline, go online to NCCN.org. NCCN makes no warranties of any kind whatsoever regarding their content, use or application and disclaims any responsibility for their application or use in any way.