Clinical Presentation

Patients with acute myeloid leukemia (AML) may present with varying combinations of the following clinical findings as a result of the accumulation of leukemic cells in the bone marrow1,2:

  • Decreases in red blood cells may cause pallor, swelling of the spleen and liver
  • Decreases in platelets may cause hemorrhage/bruising
  • Decreases in white blood cells may cause infections and fever

References: 1. Davis AD, Viera AJ, Mead MD. Leukemia: an overview for primary care. Am Fam Physician. 2014;89(9):731-738. 2. Kabel AM, Zamzami F, Al-Talhi M, Al-Dwila K, Hamza R. Acute myeloid leukemia: a focus on risk factors, clinical presentation, diagnosis and possible lines of management. J Cancer Res Treat. 2017;5(2):62-67.